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Reproductive Medicine · Gynecological Endocrinology · Endometriosis Surgery

Nicola Pluchino

MD, PhD — Geneva, Switzerland

Head of the Endometriosis Centre and the Unit of Reproductive Medicine & Gynecological Endocrinology (UMREG), Geneva University Hospitals (HUG). Privat-Docent, University of Geneva and University of Lausanne.

About

Nicola Pluchino is a physician specializing in reproductive medicine, gynecological endocrinology, and the surgical management of endometriosis. He currently heads the Endometriosis Centre and the Unit of Reproductive Medicine and Gynecological Endocrinology (UMREG) at the Geneva University Hospitals (HUG), where he also practises as a senior physician in the Department of Gynecology.

He trained in medicine at the University of Pisa, Italy, and completed clinical placements in obstetrics and gynecology internationally, including at Rotunda Hospital in Dublin, Ireland (2005), as well as in Mozambique and the United States. From 2008 to 2013 he worked full-time as a reproductive endocrinologist in the IVF unit of the University of Pisa, completing a PhD in reproductive neuroendocrinology there in 2012.

In 2016, he co-founded the first centre in French-speaking Switzerland dedicated to endometriosis, certified by the European Endometriosis League and the Endometriosis Foundation for Research. He later headed the Fertility Medicine Unit and Endometriosis Centre at the Lausanne University Hospital (CHUV) from late 2022, returning to HUG in February 2026 to direct its Endometriosis Centre and UMREG.

His academic appointments include visiting professorships at Yale University (2015–2016) and Humanitas University, Milan (2023), and Privat-Docent titles at the University of Geneva (since 2019) and University of Lausanne (since 2023). He has authored or co-authored more than 160 peer-reviewed publications in reproductive medicine and endometriosis.

Beyond the clinic and the lab, he initiated a multidisciplinary "round table" format in Switzerland — bringing together patient associations with specialists, anesthesiologists, nurses, psychiatrists, and osteopaths to work jointly on improving endometriosis care, described as one of the first initiatives of its kind in the country. He has also spoken publicly on gender medicine and the hormonal dimensions of disease and care access, including a McKinsey Health Institute discussion on closing the global women's health gap, and has written for a general audience on why endometriosis diagnosis is so often delayed.

Portrait of Dr. Nicola Pluchino
Current role
Head of Unit — Endometriosis Centre & UMREG, HUG, Geneva (Feb 2026–)
Academic title
Principal Lecturer, University of Geneva (Jun 2019–); corresponds to his 2019 Privat-Docent title
Medical degree
University of Pisa, Italy
PhD
Reproductive Neuroendocrinology, University of Pisa (2012)
Visiting professorships
Yale University School of Medicine (Sep 2015–Oct 2016); Humanitas University, Milan (2023)
Prior appointment
Head of Unit — Fertility Medicine & Endometriosis Centre, CHUV Lausanne (Nov 2022–Feb 2026)
Publications
160+ peer-reviewed articles

Clinical Focus

  • Deep infiltrating endometriosis & conservative surgery

    Laparoscopic management of severe endometriosis, including nodule shaving and discoid resection techniques aimed at preserving organ function.

  • Reproductive endocrinology & fertility medicine

    Diagnosis and treatment of infertility, including ovarian stimulation strategies for patients with reduced ovarian reserve or a poor response to treatment.

  • Endometriosis-associated infertility

    Coordinated surgical and fertility-preservation planning for patients where endometriosis and infertility intersect.

  • Reproductive ageing & perimenopause

    Clinical and research interest in hormonal changes across the reproductive lifespan, including the perimenopausal transition.

  • Sexual health in gynecological disease

    Attention to the impact of gynecological conditions, particularly endometriosis, on sexual health and quality of life.

Career

Feb 2026 —

Head of Unit, HUG (Endometriosis Centre & UMREG)

Returned to Geneva University Hospitals to direct the Endometriosis Centre and the Unit of Reproductive Medicine and Gynecological Endocrinology, alongside continued clinical practice in the Department of Gynecology.

2024 —

Founder, multidisciplinary endometriosis round table

Initiated a working-group format in Switzerland bringing together patient associations with specialists, anesthesiologists, nurses, psychiatrists, and osteopaths to jointly improve care pathways for women with endometriosis — described as one of the first initiatives of its kind in the country.

Nov 2022 – Feb 2026

Head of Unit, CHUV Lausanne

Headed the Fertility Medicine Unit and the Endometriosis Centre at the Lausanne University Hospital. Also held a Privat-Docent title at the University of Lausanne from 2023, and a visiting professorship at Humanitas University, Milan, in 2023.

Jun 2019 —

Principal Lecturer, University of Geneva

Academic appointment held continuously alongside his clinical roles at HUG and CHUV; corresponds to the Privat-Docent title conferred in 2019.

2016

Co-founder, Endometriosis Centre, HUG

Established the first centre in French-speaking Switzerland dedicated to endometriosis, later certified by the European Endometriosis League and the Endometriosis Foundation for Research (certification renewed 2023).

Sep 2015 – Oct 2016

Visiting Professor, Yale University School of Medicine

Visiting professorship in reproductive sciences, Department of Obstetrics, Gynecology and Reproductive Sciences.

Nov 2014 – Dec 2022

Medical Doctor – Ob/Gyn, HUG

Clinical role at Geneva University Hospitals, promoted to senior physician (médecin adjoint) in 2017. Note: HUG's own biography page dates his arrival to 2013 rather than late 2014 — the discrepancy likely reflects a training/rotation period versus a formal appointment date, and hasn't been resolved between the two sources.

Dec 2008 – May 2013

Reproductive Endocrinologist & IVF, University of Pisa

Full-time clinical and research role at the university's in-vitro fertilization centre, alongside his PhD in reproductive neuroendocrinology (completed 2012).

Apr – Sep 2005

Medical Doctor – Ob/Gyn, Rotunda Hospital, Dublin

Early clinical placement in obstetrics and gynecology in Ireland, part of his broader international specialty training (which also included placements in Italy, Mozambique, and the United States).

Medical degree, University of Pisa

Publications

The 10 publications below are, to the best available evidence, among Dr. Pluchino's most cited and highest-impact work. One honest caveat: Google Scholar blocks automated access to per-article citation counts, and other indexes (ResearchGate, Semantic Scholar) don't expose exact per-paper figures through an accessible page — so this ranking is an informed editorial judgment (based on journal prominence, how frequently each paper turned up cited by other work during research, and its role as a foundational reference in the field) rather than a verified citation-count ranking. For exact, current citation figures, see his Google Scholar profile linked below.
  • 2016

    Sexual function in endometriosis patients and their partners: effect of the disease and consequences of treatment

    Human Reproduction Update, 22(6), 762–774
    Pluchino N, Wenger JM, Petignat P, Tal R, Bolmont M, Taylor HS, Bianchi-Demicheli F
  • 2016

    Endometriosis and stem cell trafficking

    Reproductive Sciences, 23(12), 1616–1619
    Pluchino N, Taylor HS
  • 2019

    Adult bone marrow progenitors become decidual cells and contribute to embryo implantation and pregnancy

    PLOS Biology
    Tal R, Shaikh S, Pallavi P, et al., Pluchino N, et al., Taylor HS
  • 2020

    CXCR4 or CXCR7 antagonists treat endometriosis by reducing bone marrow cell trafficking

    Journal of Cellular and Molecular Medicine
    Pluchino N, Mamillapalli R, Shaikh S, et al., Taylor HS
  • 2018

    G-protein-coupled receptor CXCR7 is overexpressed in human and murine endometriosis

    Reproductive Sciences
    Pluchino N, Mamillapalli R, Moridi I, et al., Taylor HS
  • 2016

    A murine 5-fluorouracil-based submyeloablation model for the study of bone marrow-derived cell trafficking in reproduction

    Endocrinology
    Tal R, Liu Y, Pluchino N, et al., Taylor HS
  • 2015

    Neurobiology of DHEA and effects on sexuality, mood and cognition

    Journal of Steroid Biochemistry and Molecular Biology, 145
    Pluchino N, Drakopoulos P, Bianchi-Demicheli F, Wenger JM, Petignat P, Genazzani AR
  • 2020

    Estrogen receptor-α immunoreactivity predicts symptom severity and pain recurrence in deep endometriosis

    Fertility and Sterility
    Pluchino N, Mamillapalli R, Wenger JM, et al., Taylor HS
  • 2016

    Consensus on recording deep endometriosis surgery: the CORDES statement

    Human Reproduction
    Vanhie A, Meuleman C, Tomassetti C, et al., Pluchino N, et al., D'Hooghe T
  • 2023

    Treatment modalities for poor ovarian responders

    Therapeutic Advances in Reproductive Health
    Di Guardo F, Pluchino N, Drakopoulos P
For exact citation counts and his complete, live bibliography (180+ publications), see his profiles on Google Scholar, ResearchGate, and PubMed.

Contact

Endometriosis Centre — HUG

Boulevard de la Cluse 30, 1205 Genève, Switzerland

+41 (0)22 372 43 04

endometriose@hug.ch

Reproductive Medicine Unit (UMREG)

Fertility & gynecological endocrinology enquiries

secretariat.umreg@hug.ch

For appointments or clinical matters, please contact the HUG service directly through the channels above rather than this page. This site is a personal/professional overview, not a booking platform.